2/17/2021 – Molecular Basis of Resveratrol-Induced Resensitization of Acquired Drug-Resistant Cancer Cells – “Multidrug resistance (MDR) to anticancer drugs remains a serious obstacle to the success of cancer chemotherapy. Resveratrol, a polyphenol, present in natural products exerts anticancer activity and acts as a potential MDR inhibitor in various drug-resistant cancer cells. In the process of resensitization of drug-resistant cancer cells, resveratrol has been shown to interfere with ABC transporters and drug-metabolizing enzymes, increase DNA damage, inhibit cell cycle progression, and induce apoptosis and autophagy, as well as prevent the induction of epithelial to mesenchymal transition (EMT) and cancer stem cells (CSCs). This review summarizes the mechanisms by which resveratrol counteracts MDR in acquired drug-resistant cancer cell lines and provides a critical basis for understanding the regulation of MDR as well as the development of MDR-inhibiting drugs.” Choi CY, Lim S-C, Lee T-B, Han SI. Molecular Basis of Resveratrol-Induced Resensitization of Acquired Drug-Resistant Cancer Cells. Nutrients. 2022; 14(3):699. https://doi.org/10.3390/nu14030699
2/17/2022 – Insights into the Research Trends on Bovine Colostrum: Beneficial Health Perspectives with Special Reference to Manufacturing of Functional Foods and Feed Supplements – “Bovine colostrum (BC) is the initial mammary secretion after parturition, which is nature’s bountiful source consisting of nutritional and bioactive components present in a highly concentrated low-volume format. All mammalian newborns require colostrum to enhance physiological processes such as lifelong immunity, gastrointestinal development, and resistance to microbial infections. The genetic, environmental, and processing methods can all have an impact on the biochemical contents of BC and its supplements. BC and its derivatives have been intensively researched for their potential use in functional foods, medicines, and animal feed. Evidence from clinical studies suggests that BC products are well-tolerated, nontoxic, and safe for human ingestion. Functional foods, feed, and pharmaceutical formulations based on bovine colostrum are playing noteworthy roles in the development of innovative products for promoting health and the prevention of chronic illnesses. This systematic review sheds light on recent research on (a) the effects of processing techniques on BC components, (b) emerging techniques used in the isolation and identification of novel components, (c) BC-based functional foods for human consumption and animal feed supplements, and (d) the role of BC in current drug delivery, as well as future recommendations.” Mehra R, Garhwal R, Sangwan K, Guiné RPF, Lemos ET, Buttar HS, Visen PKS, Kumar N, Bhardwaj A, Kumar H. Insights into the Research Trends on Bovine Colostrum: Beneficial Health Perspectives with Special Reference to Manufacturing of Functional Foods and Feed Supplements. Nutrients. 2022; 14(3):659. https://doi.org/10.3390/nu14030659
2/16/2022 – A Narrative Review of the Evidence for Variations in Serum 25-Hydroxyvitamin D Concentration Thresholds for Optimal Health – “The general finding is that optimal 25(OH)D concentrations to support health and wellbeing are above 30 ng/mL (75 nmol/L) for cardiovascular disease and all-cause mortality rate, whereas the thresholds for several other outcomes appear to range up to 40 or 50 ng/mL.” Grant WB, Al Anouti F, Boucher BJ, Dursun E, Gezen-Ak D, Jude EB, Karonova T, Pludowski P. A Narrative Review of the Evidence for Variations in Serum 25-Hydroxyvitamin D Concentration Thresholds for Optimal Health. Nutrients. 2022; 14(3):639. https://doi.org/10.3390/nu14030639
2/16/2022 – Evaluating the Evidence in Clinical Studies of Vitamin D in COVID-19 – ” An upper limit vitamin D intake of 100 mcg (4000 IU) daily does not require monitoring, but higher intakes should be monitored. No harms are associated with this dose range of vitamin D, and there is potential benefit in reducing the severity of COVID-19 and risk of infection. Doses of vitamin D greater than 100 mcg (4000 IU) daily have no established role in the treatment or prevention of COVID-19, and excessive vitamin D can lead to toxicity, manifested as hypercalcemia and nephro-calcinosis.” Thacher TD. Evaluating the Evidence in Clinical Studies of Vitamin D in COVID-19. Nutrients. 2022; 14(3):464. https://doi.org/10.3390/nu14030464
12/29/2021 – Defining “Moderate” vs. “Vigorous” Exercise – According to “What is Moderate to Vigorous Exercise,” which appeared in the September 2021 open access journal Frontiers in Physiology, physical activity is defined as: “…any bodily movement produced by skeletal muscles that results in energy expenditure.” MacIntosh BR, Murias JM, Keir DA and Weir JM (2021) What Is Moderate to Vigorous Exercise Intensity? Front. Physiol. 12:682233. doi: 10.3389/fphys.2021.682233 https://www.frontiersin.org/articles/10.3389/fphys.2021.682233/full
12/29/2021 – Vitamin D and Skin Cancer: An Epidemiological, Patient-Centered Update and Review – Abstract – “Background: The current vitamin D deficiency epidemic is accompanied by an increase in endemic skin cancer. There are still multiple controversies. This review aims to give practical recommendations regarding vitamin D among people at risk or with a personal history of skin cancer. Methods: Narrative review including human research articles published between 2011 and 2021, elaborated bearing in mind an epidemiological, patient-centered approach. Results: Ultraviolet (UV) exposure (neither artificial nor natural) is not the ideal source to synthesize vitamin D. There is conflicting epidemiological evidence regarding vitamin D, non-melanoma skin cancer (NMSC), and cutaneous melanoma (CMM), confounded by the effect of sun exposure and other factors. Conclusions: Current evidence is controversial, and there are no widely applicable strategies. We propose three practical recommendations. Firstly, sun protection recommendations should be kept among people at risk or with a personal history of skin cancer. Secondly, vitamin D should preferably be sourced through diet. In patients with melanoma or at risk of cutaneous cancer, serum vitamin D checks are warranted to detect and avoid its insufficiency.” Martin-Gorgojo A, Gilaberte Y, Nagore E. Vitamin D and Skin Cancer: An Epidemiological, Patient-Centered Update and Review. Nutrients. 2021; 13(12):4292. https://doi.org/10.3390/nu13124292
12/22/2021 – Late Night Eating Adds to the Risk of Metabolic Syndrome – According to research—“A Higher Intake of Energy at Dinner Is Associated with Incident Metabolic Syndrome: A Prospective Cohort Study in Older Adults” – which appeared in the September 2021 online issue of the journal Nutrients, “neural and endocrine, as well as behavioral functions, have 24-hour rhythms and are major determinants of human metabolism” Hermenegildo-López Y, Donat-Vargas C, Sandoval-Insausti H, Moreno-Franco B, Rodríguez-Ayala M, Rey-García J, Banegas JR, Rodríguez-Artalejo F, Guallar-Castillón P. A Higher Intake of Energy at Dinner Is Associated with Incident Metabolic Syndrome: A Prospective Cohort Study in Older Adults. Nutrients. 2021; 13(9):3035. https://doi.org/10.3390/nu13093035 https://www.mdpi.com/2072-6643/13/9/3035/htm
12/15/2021 (Full Text w/ Account) – Coffee Consumption Does Not Seem to Increase Risk of Rapid Heart Rate – According to “Coffee Consumption and Incident Tachyarrhythmias Reported Behavior, Mendelian Randomization, and their Interactions,” which appeared in July 2021 online in JAMA Internal Medicine, “coffee consumption may have multiple beneficial properties, often attributed to antioxidant and anti-inflammatory effects, and is associated with reduced risks of cancer, diabetes, Parkinson disease, and overall mortality. Indeed, the benefits appear to be most pronounced when caffeinated coffee is consumed.” Kim E, Hoffmann TJ, Nah G, Vittinghoff E, Delling F, Marcus GM. Coffee Consumption and Incident Tachyarrhythmias: Reported Behavior, Mendelian Randomization, and Their Interactions. JAMA Intern Med. 2021;181(9):1185–1193. doi:10.1001/jamainternmed.2021.3616 https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2782015
12/1/2021 – Walnuts are a Life-Extension Food – According to the “Association of Walnut Consumption with Total and Cause-Specific Mortality and life Expectancy in U.S. Adults,” which appeared in the August issue of the online journal Nutrients“, “in the U.S. diet, intakes of nuts and seeds have increased from 0.5 serving/d to 0.75 serving/d from 1999 to 2012. The increased consumption of nuts partly contributed to a modest improvement in dietary quality among US adults.” Liu X, Guasch-Ferré M, Tobias DK, Li Y. Association of Walnut Consumption with Total and Cause-Specific Mortality and Life Expectancy in U.S. Adults. Nutrients. 2021;13(8):2699. Published 2021 Aug 4. doi:10.3390/nu13082699 https://pubmed.ncbi.nlm.nih.gov/34444859/
11/24/2021 – Retired NFL Players Carry Considerable Damage into Their Next Life – According to Musculoskeletal Injury History Is Associated with Lower Physical and Mental Health in a Historic Cohort of Former National Football League players, which appeared in the June 2021 issue of the Journal of Sports Rehabilitation, “as a collision sport, American football has a high risk of serious physical injury. Data from the National Football League (NFL) indicate that up to 68% of NFL players may be injured in a season.” Kerr, Zachary Y., et al. “Musculoskeletal Injury History Is Associated with Lower Physical and Mental Health in a Historical Cohort of Former National Football League Players.” Human Kinetics, Human Kinetics, 25 Jan. 2021, https://journals.humankinetics.com/view/journals/jsr/30/5/article-p760.xml. https://journals.humankinetics.com/view/journals/jsr/30/5/article-p760.xml
11/17/2021 – Short-Term, Intense Exercise Might Curtail Your Daily Step Count – In the September issue of Medicine & Science in Sports & Exercise, researchers from the Human Performance Laboratory, Department of Kinesiology and Health at the University of Texas at Austin, report that, “when completing an intense short-term exercise training program, decreasing daily background steps from 16,000 to approximately 5000 steps per day blunts some of the classic cardiometabolic adaptations to training.” Burton HM, Wolfe AS, Vardarli E, Satiroglu R, Coyle EF. Background Inactivity Blunts Metabolic Adaptations to Intense Short-Term Training. Med Sci Sports Exerc. 2021;53(9):1937-1944. doi:10.1249/MSS.0000000000002646 https://pubmed.ncbi.nlm.nih.gov/34398061/
11/10/2021 – Edible Mushrooms May Lower Risk of Depression – “From a premature death standpoint, “adults who ate mushrooms had a lower risk of premature death, regardless of their demographics, lifestyle choices, and other dietary factors,” according to Penn State College of Medicine News.” Ba, D. M., Gao, X., Al-Shaar, L., Muscat, J. E., Chinchilli, V. M., Beelman, R. B., & Richie, J. P. (2021, July 22). Mushroom intake and depression: A population-based study using data from the US National Health and Nutrition Examination Survey (NHANES), 2005–2016. Journal of Affective Disorders. https://www.sciencedirect.com/science/article/abs/pii/S016503272100759X?via%3Dihub. https://doi.org/10.1016/j.jad.2021.07.080
11/3/2021 – The Amino Acid Glutamine Is Another Weapon for COVID-19 Prevention – “A diverse group of researchers – Japan, China, and United States, report in Cell Death & Differentiation (CDD) in October 2021– “Comorbidity-Associated Glutamine Deficiency Is a Predisposition to Severe COVID-19” – that, “while it is presently unclear whether glutamine supplementation post-infection leads to an overall positive outcome, addressing glutamine deficiency prophylactically for those in high-risk groups is a safe and simple strategy for their protection in the era of COVID-19.” Matsuyama, T., Yoshinaga, S.K., Shibue, K. et al. Comorbidity-associated glutamine deficiency is a predisposition to severe COVID-19. Cell Death Differ (2021). https://doi.org/10.1038/s41418-021-00892-y
10/27/2021 – Nutritional Supplementation with Resistance Exercise Increases Lean Muscle – “According to “The Effect of a Multi-Ingredient Supplement on Resistance Training-Induced Adaptations,” which appeared in the August issue of Medicine & Science in Sports & Exercise, “leucine is a critical amino acid for increasing MPS and suppressing muscle protein breakdown. It is unique among amino acids in its ability to independently stimulate MPS through activation of the mechanistic target of rapamycin complex 1 pathway.” Wageh M, Fortino SA, McGlory C, Kumbhare D, Phillips SM, Parise G. The Effect of a Multi-ingredient Supplement on Resistance Training-induced Adaptations. Med Sci Sports Exerc. 2021;53(8):1699-1707. doi:10.1249/MSS.0000000000002641 https://journals.lww.com/acsm-msse/Abstract/2021/08000/The_Effect_of_a_Multi_ingredient_Supplement_on.18.aspx
9/1/2021 – Maximum Wellness, Episode 114: Young Swimmers Are at Increased Risk to Overtraining Injury – “According to Swim-Training Volume and Shoulder Pain Across the Life Span of the Competitive Swimmer: A Systemic Review, which appeared in the January 2020 issue of the Journal of Athletic Training, “injuries in competitive swimming primarily arise from repetitive strain and microtrauma. This is not surprising, when one considers the amount of swimming to which the athletes are exposed.” Feijen S, Tate A, Kuppens K, Claes A, Struyf F. Swim-Training Volume and Shoulder Pain Across the Life Span of the Competitive Swimmer: A Systematic Review. J Athl Train. 2020;55(1):32-41. doi:10.4085/1062-6050-439-18 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961642/
8/26/2021 – Maximum Wellness, Episode 113: Determining the Correct Diet Post Cancer Diagnosis – “According to “The Facts About Food After Cancer Diagnosis: A Systematic Review of Prospective Cohort Studies,” which appeared in the August 2020 issue of the online, peer reviewed journal Nutrients, “to prevent malnutrition, energy and protein requirements for cancer patients are largely widespread by international guidelines, but little is known about the food choices and dietary regimen a cancer patient should benefit from.” Rinninella E, Mele MC, Cintoni M, Raoul P, Ianiro G, Salerno L, Pozzo C, Bria E, Muscaritoli M, Molfino A, Gasbarrini A. The Facts about Food after Cancer Diagnosis: A Systematic Review of Prospective Cohort Studies. Nutrients. 2020; 12(8):2345. https://doi.org/10.3390/nu12082345 https://www.mdpi.com/2072-6643/12/8/2345/htm
8/16/2021 – Nutrition & Physical Activity May Modify Covid-19 Risk – “The study – Nutrition in the Actual Covid-19 Pandemic. A Narrative Review – which appeared in the June online issue of Nutrients, found that the COVID-19 lockdown promoted unhealthy dietary changes and increases in body weight of the population, showing obesity and low physical activity levels, as increased risk factors of COVID-19 affection and physiopathology.” Clemente-Suárez VJ, Ramos-Campo DJ, Mielgo-Ayuso J, Dalamitros AA, Nikolaidis PA, Hormeño-Holgado A, Tornero-Aguilera JF. Nutrition in the Actual COVID-19 Pandemic. A Narrative Review. Nutrients. 2021; 13(6):1924. https://doi.org/10.3390/nu13061924 https://www.mdpi.com/2072-6643/13/6/1924/htm
8/9/2021 – Nutritional Factors May Modify Risk to Covid-19 – With respect to Covid-19 and the association of dietary behaviors, researchers from the Department of Preventive Medicine, Research and Information Services, and the Department of Medicine, Feinberg School of Medicine, Northwestern University in Chicago, chose to use data from the UK Biobank (UKB) to examine the dietary behaviors measured in 2006-2010 and Covid-19 infections in 2020. Vu T-HT, Rydland KJ, Achenbach CJ, Van Horn L, Cornelis MC. Dietary Behaviors and Incident COVID-19 in the UK Biobank. Nutrients. 2021; 13(6):2114. https://doi.org/10.3390/nu13062114 https://www.mdpi.com/2072-6643/13/6/2114/htm
7/28/2921 – Maximum Wellness, Episode 109: Green Tea & Coffee Consumption May Hold Benefits for Type-2 Diabetics – ” Japanese researchers publishing the “Additive Effects of Green Tea and Coffee on All-Cause Mortality in Patients with Type-2 Diabetes Mellitus: the Fukuoka Diabetes Registry”, which appeared in October 2020 in the open-access online BMJ (British Medical Journal) Diabetes Research & Care, determined that, “higher consumption of green tea and coffee was associated with reduced all-cause mortality: their combined effect appeared to be additive in patients with type-2 diabetes.””, et al Additive effects of green tea and coffee on all-cause mortality in patients with type 2 diabetes mellitus: the Fukuoka Diabetes Registry
7/20/2021 – Lean & Hard: Creatine Monohydrate for Older Adults – New research – Current Evidence and Possible Future Applications of Creatine Supplementation for Older Adults – which appeared in the March 2021 online, peer- reviewed journal Nutrients – comments that, “sarcopenia typically occurs in 8–13% of adults ≥60 years of age, and, is associated with other age-related health conditions, such as osteoporosis, osteosarcopenia (muscle related bone loss), sarcopenic obesity, physical frailty, and cachexia (muscle loss due to disease).” Candow DG, Forbes SC, Kirk B, Duque G. Current Evidence and Possible Future Applications of Creatine Supplementation for Older Adults. Nutrients. 2021;13(3):745. Published 2021 Feb 26. doi:10.3390/nu13030745 https://pubmed.ncbi.nlm.nih.gov/33652673/
7/20/2021 – Covid Infected Pro Athletes & Inflammatory Heart Disease – In new research – Prevalence of Inflammatory Heart Disease Among Professional Athletes with Prior COVID-19 Infection Who Received Systemic Return-to-Play Cardiac Screening – which appeared in March of 2021 in the online issue of JAMA Cardiology (Journal of the American College of Cardiology), a diverse group of medical experts sought to, “to assess the prevalence of detectable inflammatory heart disease in professional athletes with prior COVID-19 infection, using current RTP screening recommendations.” Martinez MW, Tucker AM, Bloom OJ, et al. Prevalence of Inflammatory Heart Disease Among Professional Athletes With Prior COVID-19 Infection Who Received Systematic Return-to-Play Cardiac Screening. JAMA Cardiol. 2021;6(7):745-752. doi:10.1001/jamacardio.2021.0565 https://jamanetwork.com/journals/jamacardiology/fullarticle/2777308
7/12/2021 – Chocolate Helps to Control Hunger and Appetite in Postmenopausal Women – Research – Timing of Chocolate Intake Affects Hunger, Substrate Oxidation, and Microbiota: a Randomized Controlled Trail – reported in the July online issue of the FASEB journal (the journal of the Federation of American Societies for Experimental Biology), suggests that, “chocolate, in the morning or in the evening/night, in a narrow window of time (1 hour), results in differential effects on hunger and appetite, substrate oxidation, fasting glucose, microbiota composition and function, and sleep and temperature rhythms.” Hernández-González T, González-Barrio R, Escobar C, et al. Timing of chocolate intake affects hunger, substrate oxidation, and microbiota: A randomized controlled trial. FASEB J. 2021;35(7):e21649. doi:10.1096/fj.202002770RR https://faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202002770RR
6/22/2021 – Metabolic Syndrome: How Exercise Can Be Medicine – “University researchers in Spain, reporting in the July 2021 issue of Medicine & Science in Sports & Exercise, sought to determine the effects of a 5-year exercise intervention on MetS, health-related variables, and medication use. Using a randomized, controlled trial, 64 middle-age men and women with MetS, who were physically inactive (less than150 minutes per week of moderate-intensity physical activity) were allocated to three alternate day exercise sessions per week or a standard care group – with a block on age, number of MetS factors, and body mass index (BMI).” Morales-Palomo F, Moreno-Cabañas A, Ramirez-Jimenez M, et al. Exercise Reduces Medication for Metabolic Syndrome Management: A 5-Year Follow-up Study. Med Sci Sports Exerc. 2021;53(7):1319-1325. doi:10.1249/MSS.0000000000002591 https://journals.lww.com/acsmmsse/Fulltext/2021/07000/Exercise_Reduces_Medication_for_Metabolic_Syndrome.1.aspx
6/16/2021 – Physical Activity May Protect Against Breast & Prostate Cancer Risk – “Current research – Effect of Time of Day of Recreational and Household Physical Activity on Prostate and Breast Cancer Risk (MCC-Spain Study) – which appeared in the September 2020 issue of the International Journal of Cancer, said, “a recent meta‐analysis on breast cancer reported an approximate 20% reduction in risk associated with physical exercise for both premenopausal and postmenopausal women.” Weitzer J, Castaño-Vinyals G, Aragonés N, et al. Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC-Spain study). Int J Cancer. 2021;148(6):1360-1371. doi:10.1002/ijc.33310 https://pubmed.ncbi.nlm.nih.gov/32976649/
6/11/2021 – Waist-to-Height Ratio’s (WHtR) Connection to Disease – JAMA (Journal of the American Medical Association) Cardiology in July of 2019 said, “normal-weight central obesity in women (postmenopausal) was associated with excess risk of mortality, similar to that of women with BMI-defined obesity with central obesity.” Sun Y, Liu B, Snetselaar LG, et al. Association of Normal-Weight Central Obesity With All-Cause and Cause-Specific Mortality Among Postmenopausal Women. JAMA Netw Open. 2019;2(7):e197337. Published 2019 Jul 3. doi:10.1001/jamanetworkopen.2019.7337 https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2738622
6/10/2021 – Preserving Muscle Mass & Strength in Elderly With Resistance Exercise Plus Creatine – The combined myopenic and dynapenic state is called sarcopenia, that according to research – Creatine Supplementation During Resistance Training in Older Adults –a Meta-Analysis, which appeared in 2014 in Medicine & Science in Sports & Exercise, “is characterized by type II muscle fiber atrophy, myofiber necrosis, and myofiber type grouping, and increased intramuscular content of non-muscle tissue, such as intramyocellular lipid and connective tissue.” Devries MC, Phillips SM. Creatine supplementation during resistance training in older adults-a meta-analysis. Med Sci Sports Exerc. 2014;46(6):1194-1203. doi:10.1249/MSS.0000000000000220 https://journals.lww.com/acsm-msse/Fulltext/2014/06000/Creatine_Supplementation_during_Resistance.16.aspx
6/8/2021 – Vitamin D and Lung Outcomes in Elderly COVID-19 Patients – “Vitamin D deficiency is frequently reported in patients with SARS-CoV-2 infection. The aim of this study was to correlate the 25OH-Vitamin D serum concentrations with clinical parameters of lung involvement, in elderly patients hospitalized for SARS-CoV-2 infection.” Sulli A, Gotelli E, Casabella A, et al. Vitamin D and Lung Outcomes in Elderly COVID-19 Patients. Nutrients. 2021;13(3):717. Published 2021 Feb 24. doi:10.3390/nu13030717
6/1/2021 – Age Gracefully: Combat Skin Aging with Your Diet – “According to Boosting the Photoaged Skin: The Potential Role of Dietary Components, which appeared in the May 2021 online issue of the journal Nutrients, “skin photoaging is caused by long-term exposure to ultraviolet (UV), and manifests as rough, dry, and sagging skin, deeper skin wrinkles, excessive skin pigmentation, or angiotelectasis, even leading to various benign or malignant tumors, such as solar keratosis, squamous cell carcinoma, and malignant melanoma.”” Geng R, Kang SG, Huang K, Tong T. Boosting the Photoaged Skin: The Potential Role of Dietary Components. Nutrients. 2021;13(5):1691. Published 2021 May 16. doi:10.3390/nu13051691 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156873/
6/1/2021 – (Free Download w/ Account) – Association Between Achieved ω-3 Fatty Acid Levels and Major Adverse Cardiovascular Outcomes in Patients With High Cardiovascular Risk: A Secondary Analysis of the STRENGTH Trial – “Key Points – Question: In statin-treated patients at high cardiovascular risk with elevated triglyceride levels and low levels of high-density lipoprotein cholesterol treated with ω-3 fatty acids, are achieved levels of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) associated with cardiovascular outcomes? Findings: In a secondary analysis of a randomized clinical trial studying a carboxylic acid formulation of ω-3 fatty acids, plasma levels of EPA and DHA were measured 12 months after randomization in 10 382 patients. There was no association between achieved or change in level of either ω-3 fatty acid and major adverse cardiovascular events.” Nissen SE, Lincoff AM, Wolski K, et al. Association Between Achieved ω-3 Fatty Acid Levels and Major Adverse Cardiovascular Outcomes in Patients With High Cardiovascular Risk: A Secondary Analysis of the STRENGTH Trial [published online ahead of print, 2021 May 16]. JAMA Cardiol. 2021;e211157. doi:10.1001/jamacardio.2021.1157
5/27/2021 (Update) – The Ketogenic Diet Is More Than Just Weight-Loss – According to the Nutrients research – The Potential Health Benefits of the Ketogenic Diet: A Narrative review – “recent studies utilizing Low-carbohydrate, High-fat (LCHF) diets, such as the ketogenic diet, show promise in helping patients lose weight, reverse the signs of metabolic syndrome, reduce, or eliminate insulin requirements for type II diabetics, reduce inflammation, improve epigenetic profiles, alter the microbiome, improve lipid profiles, supplement cancer treatments, and potentially increase longevity and brain function.”” Dowis K, Banga S. The Potential Health Benefits of the Ketogenic Diet: A Narrative Review. Nutrients. 2021; 13(5):1654. https://doi.org/10.3390/nu13051654 https://www.mdpi.com/2072-6643/13/5/1654/htm
5/13/2021 – A Ketogenic Diet Has Benefits for Body Builders – New research – Effects of Two Months of Very Low Carbohydrate Ketogenic Diet on Body composition, Muscle Strength, Muscle Area, and Blood Parameters in Competitive Body Builders – which appeared in the January 2021, online issue of the journal Nutrients, tested the outcome of a KD diet on nineteen, experienced, male body builders (BB) between the ages of 20 to 40, allocated to a KD diet and control group, who followed a western-type diet (WD). Paoli A, Cenci L, Pompei P, Sahin N, Bianco A, Neri M, Caprio M, Moro T. Effects of Two Months of Very Low Carbohydrate Ketogenic Diet on Body Composition, Muscle Strength, Muscle Area, and Blood Parameters in Competitive Natural Body Builders. Nutrients. 2021; 13(2):374. https://doi.org/10.3390/nu13020374 https://www.mdpi.com/2072-6643/13/2/374/htm
5/5/2021 – Maximum Wellness, Episode 97: Vitamin D Reduces Covid-19 Risk in an Aged Population – This study – “Relation Between Vitamin D and Covid-19 in Aged People: A Systematic Review” – which appeared in the April 2021 issue of the online, peer reviewed journal Nutrients, used 707 studies identified to assess adverse outcomes and the benefits of Vitamin D supplementation for people 60 years and older with Covid-19 exposure. Studies included data from aged patients on vitamin D use and Covid-19, while basic science articles, editorials, and correspondence was excluded from the analysis. Dramé M, Cofais C, Hentzien M, et al. Relation between Vitamin D and COVID-19 in Aged People: A Systematic Review. Nutrients. 2021;13(4):1339. Published 2021 Apr 17. doi:10.3390/nu13041339 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073922/
4/30/2021 – (Abstract Only) Isolated Leucine and Branched-Chain Amino Acid Supplementation for Enhancing Muscular Strength and Hypertrophy: A Narrative Review – Branched-chain amino acids (BCAA) are one of the most popular sports supplements, marketed under the premise that they enhance muscular adaptations. Despite their prevalent consumption among athletes and the general public, the efficacy of BCAA has been an ongoing source of controversy in the sports nutrition field. Early support for BCAA supplementation was derived from extrapolation of mechanistic data on their role in muscle protein metabolism. Of the three BCAA, leucine has received the most attention because of its ability to stimulate the initial acute anabolic response. However, a substantial body of both acute and longitudinal research has now accumulated on the topic, affording the ability to scrutinize the effects of BCAA and leucine from a practical standpoint. This article aims to critically review the current literature and draw evidence-based conclusions about the putative benefits of BCAA or leucine supplementation on muscle strength and hypertrophy as well as illuminate gaps in the literature that warrant future study. Plotkin DL, Delcastillo K, Van Every DW, Tipton KD, Aragon AA, Schoenfeld BJ. Isolated Leucine and Branched-Chain Amino Acid Supplementation for Enhancing Muscular Strength and Hypertrophy: A Narrative Review [published online ahead of print, 2021 Mar 18]. Int J Sport Nutr Exerc Metab. 2021;1-10. doi:10.1123/ijsnem.2020-0356
4/28/2021 – Maximum Wellness, Episode 96: Resistance Exercise Improves Post-Meal Glucose Levels in Prediabetic Men – According to research – a “Single Bout of Premeal Resistance Exercise Improves Postprandial Glucose Metabolism in Obese Men with Prediabetes” – which appeared in the April 2021 issue of Medicine & Science in Sports & Exercise, the (2002) Diabetes Prevention Program Research Study demonstrated that lifestyle interventions, which targeted a 7% weight loss with 150 minutes per week of moderate-intensity endurance exercise, “reduced the incidence of T2D by 58% and was significantly more effective than treatment with metformin alone in individuals with prediabetes.” Bittel AJ, Bittel DC, Mittendorfer B, et al. A Single Bout of Premeal Resistance Exercise Improves Postprandial Glucose Metabolism in Obese Men with Prediabetes. Med Sci Sports Exerc. 2021;53(4):694-703. doi:10.1249/MSS.0000000000002538 https://journals.lww.com/acsm-msse/Abstract/2021/04000/A_Single_Bout_of_Premeal_Resistance_Exercise.3.aspx
4/27/2021 – Vitamin D May Reduce Covid-19 Risk in an Aged Population – This study – Relation Between Vitamin D and Covid-19 in Aged People: A Systematic Review – which appeared in the April 2021issue of the online, peer reviewed journal Nutrients, used 707 studies identified to assess adverse outcomes and the benefits of Vitamin D supplementation for people 60 years and older with Covid-19 exposure. Studies included data from aged patients on vitamin D use and Covid-19, while basic science articles, editorials, and correspondence was excluded from the analysis. Dramé M, Cofais C, Hentzien M, Proye E, Coulibaly PS, Demoustier-Tampère D, Destailleur M-H, Lotin M, Cantagrit E, Cebille A, Desprez A, Blondiau F, Kanagaratnam L, Godaert L. Relation between Vitamin D and COVID-19 in Aged People: A Systematic Review. Nutrients. 2021; 13(4):1339. https://doi.org/10.3390/nu13041339 https://www.mdpi.com/2072-6643/13/4/1339/htm
4/22/2021 – Maximum Wellness, Episode 95: Diet May Play a Part in Lower Testosterone in Men – In the February 2020 online issue of the Journal of Urology, a study – “The Association Between Popular Diets and Serum Testosterone Among Men in the United States” – concluded that, “men adhering to low fat diets had lower serum testosterone levels, even when controlling for comorbidities, age, body mass index, and activity levels.” Fantus RJ, Halpern JA, Chang C, et al. The Association between Popular Diets and Serum Testosterone among Men in the United States. J Urol. 2020;203(2):398-404. doi:10.1097/JU.0000000000000482 https://www.auajournals.org/doi/10.1097/JU.0000000000000482
4/14/2021 – Maximum Wellness, Episode 94: Collagen Peptides May Reduce Knee Injury Pain – According to research – “The Influence of Specific Bioactive Collagen Peptides on Knee Joint Discomfort in Young, Physically Active Adults: A Randomized Controlled Trial” – which appeared in the February 2021 issue of the online journal Nutrients, “collagen type I and II are the most important structural and functional components of the extracellular matrix of tendons, ligaments and cartilage.” Zdzieblik, D., Brame, J., Oesser, S., Gollhofer, A., & König, D. (2021). The Influence of Specific Bioactive Collagen Peptides on Knee Joint Discomfort in Young Physically Active Adults: A Randomized Controlled Trial. Nutrients, 13(2), 523. https://doi.org/10.3390/nu13020523 https://www.mdpi.com/2072-6643/13/2/523
3/31/2021 – Maximum Wellness, Episode 92: L-Glutamine May Reduce the Severity of Covid-19 in Hospital Patients – According to research – Effect of Oral L-Glutamine Supplementation on Covid-19 Treatment, which appeared in the July 2020, open science journal Clinical Nutrition Experimental – researchers from Biruni University Faculty of Medicine in Afghanistan – conclude that, “adding enteral L-Glutamine to the normal nutrition in the early period of Covid-19 infection, may lead to a shortened hospital stay and lead to less need for ICU.” Cengiz M, Borku Uysal B, Ikitimur H, et al. Effect of oral l-Glutamine supplementation on Covid-19 treatment. Clin Nutr Exp. 2020;33:24-31. doi:10.1016/j.yclnex.2020.07.003 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387270/
3/23/2021 – Maximum Wellness, Episode 91: Essential Amino Acids Support Muscle Protein Synthesis – “According to “Essential Amino Acids and Protein Synthesis: Insights into Maximizing the Muscle and Whole-Body Response to Feeding,” which appeared in the December 2020 issue of the online, peer-reviewed journal Nutrients, “intracellular amino acid recycling is not 100% efficient.” MPB can exceed MPS in the post-absorptive state, resulting in a net loss of muscle protein.” Church DD, Hirsch KR, Park S, et al. Essential Amino Acids and Protein Synthesis: Insights into Maximizing the Muscle and Whole-Body Response to Feeding. Nutrients. 2020;12(12):3717. Published 2020 Dec 2. doi:10.3390/nu12123717 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760188/
3/10/2021 – African Americans with Low Vitamin D Status Have Increased Covid-19 Risk– “African Americans have higher incidence of, and mortality from, many health-related problems than European Americans. They also have a 15 to 20-fold higher prevalence of severe vitamin D deficiency.” Ames BN, Grant WB, Willett WC. Does the High Prevalence of Vitamin D Deficiency in African Americans Contribute to Health Disparities? Nutrients. 2021; 13(2):499. https://doi.org/10.3390/nu13020499 https://www.mdpi.com/2072-6643/13/2/499/htm
3/8/2021 – Greater Loss of Central Adiposity from Low-Carbohydrate versus Low-Fat Diet in Middle-Aged Adults with Overweight and Obesity – “The objective of this study is to determine whether middle-aged adults prescribed a low carbohydrate-high fat (LCHF) or low fat (LF) diet would have greater loss of central fat and to determine whether the insulin resistance (IR) affects intervention response.” Garr Barry V, Stewart M, Soleymani T, Desmond RA, Goss AM, Gower BA. Greater Loss of Central Adiposity from Low-Carbohydrate versus Low-Fat Diet in Middle-Aged Adults with Overweight and Obesity. Nutrients. 2021; 13(2):475. https://doi.org/10.3390/nu13020475
3/8/2021 – Micronutrients, Phytochemicals and Mediterranean Diet: A Potential Protective Role against COVID-19 through Modulation of PAF Actions and Metabolism – The new coronavirus disease 2019 (COVID-19) pandemic is an emerging situation with high rates of morbidity and mortality, in the pathophysiology of which inflammation and thrombosis are implicated. The disease is directly connected to the nutritional status of patients and a well-balanced diet is recommended by official sources.” Detopoulou P, Demopoulos CA, Antonopoulou S. Micronutrients, Phytochemicals and Mediterranean Diet: A Potential Protective Role against COVID-19 through Modulation of PAF Actions and Metabolism. Nutrients. 2021; 13(2):462. https://doi.org/10.3390/nu13020462
3/8/2021 – Magnesium in Aging, Health and Diseases – “Several changes of magnesium (Mg) metabolism have been reported with aging, including diminished Mg intake, impaired intestinal Mg absorption and renal Mg wasting. Mild Mg deficits are generally asymptomatic and clinical signs are usually non-specific or absent.” Barbagallo M, Veronese N, Dominguez LJ. Magnesium in Aging, Health and Diseases. Nutrients. 2021; 13(2):463. https://doi.org/10.3390/nu13020463
3/8/2021 – Collagen Peptides Reduce Pain Associated with Knee Injury – “Once tissue or a joint is damaged, inflammation, a normal reaction to trauma, is initiated, which can be associated with pain. “Regardless of whether muscles, tendons or cartilage tissue are affected, the cause is a disproportion between load and load tolerance of the tissue,” as noted in the Nutrient’s paper.” Zdzieblik D, Brame J, Oesser S, Gollhofer A, König D. The Influence of Specific Bioactive Collagen Peptides on Knee Joint Discomfort in Young Physically Active Adults: A Randomized Controlled Trial. Nutrients. 2021; 13(2):523. https://doi.org/10.3390/nu13020523 https://www.mdpi.com/2072-6643/13/2/523
3/6/2021 – Magnesium in Obesity, Metabolic Syndrome, and Type 2 Diabetes – “Magnesium (Mg2+) deficiency is probably the most underestimated electrolyte imbalance in Western countries. It is frequent in obese patients, subjects with type-2 diabetes and metabolic syndrome, both in adulthood and in childhood. This narrative review aims to offer insights into the pathophysiological mechanisms linking Mg2+ deficiency with obesity and the risk of developing metabolic syndrome and type 2 diabetes. Literature highlights critical issues about the treatment of Mg2+ deficiency, such as the lack of a clear definition of Mg2+ nutritional status, the use of different Mg2+” Piuri G, Zocchi M, Della Porta M, Ficara V, Manoni M, Zuccotti GV, Pinotti L, Maier JA, Cazzola R. Magnesium in Obesity, Metabolic Syndrome, and Type 2 Diabetes. Nutrients. 2021; 13(2):320. https://doi.org/10.3390/nu13020320
3/3/2021 – 8500 Daily steps reduce a high-fat meal risk to cardiovascular disease – “According to “Clinical Relevance of Non-Fasting and Postprandial Hypertriglyceridemia and Remnant Cholesterol,” which appeared in 2011 on PubMed.gov, “non-fasting triglycerides are measured at any time within up to 8 hours, after any normal meal, while postprandial triglycerides are measured at a fixed time point within up to 8 hours of a standardized fat tolerance test.”” Nordestgaard BG, Freiberg JJ. Clinical relevance of non-fasting and postprandial hypertriglyceridemia and remnant cholesterol. Curr Vasc Pharmacol. 2011;9(3):281-286. doi:10.2174/157016111795495585 https://pubmed.ncbi.nlm.nih.gov/21314630/
2/24/2021 – Maximum Wellness, Episode 87: Maximizing Recovery from Training & Competition – “In a study – “Co-Ingestion of Carbohydrate and Protein on Muscle Glycogen Synthesis After Exercise: A Meta-Analysis” – which was reported in the February 2021 issue of Medicine & Science in Sports & Exercise, researchers from the Military Nutrition Division, U.S. Army Research Institute of Environmental Medicine in Massachusetts, and the Oak Ridge Institute of Science and Education, in Tennessee, the primary objective was, “to aggregate results from multiple studies to characterize the effects of CHO-PRO on glycogen synthesis, during recovery from exercise compared with CHO alone.”” Margolis LM, Allen JT, Hatch-McChesney A, Pasiakos SM. Coingestion of Carbohydrate and Protein on Muscle Glycogen Synthesis after Exercise: A Meta-analysis. Med Sci Sports Exerc. 2021;53(2):384-393. doi:10.1249/MSS.0000000000002476 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803445/
2/18/2021 – High Intensity Interval Exercise VS Moderate Intensity, Continuous Training – “Writing in the March 2021 issue of Medicine & Science in Sports & Exercise – Effectiveness of HIIE versus MICT in Improving Cardiometabolic Risk Factors in Health and Disease: a Meta-Analysis – researchers from the Sports Medicine Department, Clinical Epidemiology and Applied Biometrics Department, and the Psychosomatic Medicine and Psychotherapy Department, University Hospital of Tubingen in Germany, used a meta-analysis (many similar studies) to investigate the clinical benefits distinguishing each exercise modality (HIIE and MICT) in health and disease.” MATTIONI MATURANA, FELIPE1; MARTUS, PETER2; ZIPFEL, STEPHAN3; NIEß, ANDREAS M.1 Effectiveness of HIIE versus MICT in Improving Cardiometabolic Risk Factors in Health and Disease: A Meta-analysis, Medicine & Science in Sports & Exercise: March 2021 – Volume 53 – Issue 3 – p 559-573
doi: 10.1249/MSS.0000000000002506
Effectiveness of HIIE versus MICT in Improving Cardiometabol… : Medicine & Science in Sports & Exercise (lww.com)
2/17/2021 – Maximum Wellness, Episode 86: Omega-3 Polyunsaturated Fatty Acid Update – “According to “An Update on Omega-3 Polyunsaturated Fatty Acids and Cardiovascular Health”, which appeared in the January 2021 online, peer-reviewed journal Nutrients, “TG levels are a historically well-studied, independent risk factor for CHD. Ω-3 (omega-3) or fish oil diet supplementation is evidenced to lower TG levels in a dose-dependent fashion, whereby 3–4 g/day of eicosapentaenoic acid (EPA), or a combined EPA and docosahexaenoic acid (DHA) reduces blood levels by 20–50% in those with high TG’s.”” Elagizi A, Lavie CJ, O’Keefe E, Marshall K, O’Keefe JH, Milani RV. An Update on Omega-3 Polyunsaturated Fatty Acids and Cardiovascular Health. Nutrients. 2021;13(1):204. Published 2021 Jan 12. doi:10.3390/nu13010204 An Update on Omega-3 Polyunsaturated Fatty Acids and Cardiovascular Health (nih.gov)
2/16/2021 – L-Gutamine May Reduce the Severity of Covid-19 “According to research – Effect of Oral L-Glutamine Supplementation on Covid-19 Treatment, which appeared in the July 2020, open science journal Clinical Nutrition Experimental – researchers from Biruni University Faculty of Medicine in Afghanistan – conclude that, “adding enteral L-Glutamine to the normal nutrition in the early period of Covid-19 infection may lead to a shortened hospital stay and lead to less need for ICU.”” https://www.clinicalnutritionopenscience.com/article/S2352-9393(20)30016-6/fulltext
2/9/2021 – Time-Restricted Eating Offers Many Beneficial Health Effects – “According to Food Timing, Circadian Rhythm and Chrononutrition: A Systematic review of Time-Restricted Eating’s Effects on Human Health, which appeared in the December 2020 issue of the online, peer-reviewed journal Nutrients , “a recent systematic review and meta-analysis of 19 studies showed that TRE leads to weight loss and a reduction in fat mass with a preservation of fat-free mass and also has beneficials effects on cardiometabolic parameters such as blood pressure, fasting glucose concentration and cholesterol profiles.”” Adafer R, Messaadi W, Meddahi M, Patey A, Haderbache A, Bayen S, Messaadi N. Food Timing, Circadian Rhythm and Chrononutrition: A Systematic Review of Time-Restricted Eating’s Effects on Human Health. Nutrients. 2020; 12(12):3770. https://doi.org/10.3390/nu12123770 https://www.mdpi.com/2072-6643/12/12/3770
2/9/2021 – Controlling Your Stress and Your Magnesium Intake – “According to research – Magnesium Status and Stress: The Vicious Circle Concept Revisited – which appeared in the January 2021 issue of the online, peer-reviewed journal Nutrients, “magnesium is a naturally occurring calcium channel blocker, is involved in the maintenance of electrolyte balance (e.g., regulation of sodium–potassium ATPase activity), and plays a key role in membrane excitability.”” Pickering G, Mazur A, Trousselard M, Bienkowski P, Yaltsewa N, Amessou M, Noah L, Pouteau E. Magnesium Status and Stress: The Vicious Circle Concept Revisited. Nutrients. 2020; 12(12):3672. https://doi.org/10.3390/nu12123672 https://www.mdpi.com/2072-6643/12/12/3672
2/8/2021 – Should You Eat Before Endurance Exercise? – “Researchers at the Sports Performance Research Institute and the Auckland University of Technology in New Zealand comment in, What Should I Eat Before Exercise? Pre-Exercise Nutrition and Response to Endurance Exercise: Current Prospective and Future directions, which appeared in November 2020 issue of the journal Nutrients, that, “despite being relevant to anyone performing exercise, many questions relating to the effects of nutritional intake on endurance training responses and adaptations remain unanswered.”” Rothschild JA, Kilding AE, Plews DJ. What Should I Eat before Exercise? Pre-Exercise Nutrition and the Response to Endurance Exercise: Current Prospective and Future Directions. Nutrients. 2020;12(11):3473. Published 2020 Nov 12. doi:10.3390/nu12113473 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696145/
12/29/2020 – You are as Young as You’re Metabolically Active – “The Importance of Fatty Acids as Nutrients During Post-Exercise Recovery, which appeared in the March online issue of the journal Nutrients, “the peak in circulating FA concentration in the immediate recovery (first hour post-exercise) period following submaximal exercise hcas been suggested to be due to a delayed spill-over effect from the increased adipose tissue lipolysis (fatty acid breakdown) induced during exercise.”” Lundsgaard AM, Fritzen AM, Kiens B. The Importance of Fatty Acids as Nutrients during Post-Exercise Recovery. Nutrients. 2020;12(2):280. Published 2020 Jan 21. doi:10.3390/nu12020280 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070550/
2/1/2020 – Vitamins and Minerals to Improve Adolescent Fitness – The study, originally featured in the Journal of Applied Physiology and described in Life Extension online, says that adolescents performed better on fitness exercise tests when they had higher amounts of vitamins and minerals in the blood. The researchers from the University of Zaragozo in Spain, https://www.lifeextension.com/newsletter/2012/8/increased-levels-of-vitamins-and-iron-linked-with-better-physical-fitness-during-adolescence
12/18/2020 – Vitamin D Status and its Association with COVID-19 Severity – “Researchers from the Department of Internal Medicine, University of Heidelberg, Germany, report in the September issue of the online, peer-reviewed journal Nutrients, an association between vitamin D deficiency and the severity/mortality of COVID-19 – which, they say, highlights the need for interventional studies on vitamin D supplementation in SARS-CoV-2 infected individuals.” Radujkovic A, Hippchen T, Tiwari-Heckler S, Dreher S, Boxberger M, Merle U. Vitamin D Deficiency and Outcome of COVID-19 Patients. Nutrients. 2020; 12(9):2757. https://doi.org/10.3390/nu12092757 https://www.mdpi.com/2072-6643/12/9/2757
1/8/2021 – Vitamin D & Calcium: Fighting Gestational Diabetes – “A new study out of Isfahan University of Medical Sciences in Iran reports that the combination of vitamin D and calcium may help combat the problem. Their research study looked at 56 pregnant women with gestational diabetes mellitus” Asemi Z, Karamali M, Esmaillzadeh A. Effects of calcium-vitamin D co-supplementation on glycaemic control, inflammation and oxidative stress in gestational diabetes: a randomised placebo-controlled trial. Diabetologia. 2014;57(9):1798-1806. doi:10.1007/s00125-014-3293-x https://pubmed.ncbi.nlm.nih.gov/24962666/
2/1/2020 – Top Five Ways To Remove Stress From Your Life – According to a new report from the Harvard Health Publication, however, ways to cut stress from your life are within your control. The report describes how studies indicate a direct link between stress and heart disease and stroke. https://www.health.harvard.edu/mind-and-mood/best-ways-to-manage-stress
2/1/2020 – Top Five Ways to Prolong Your Life – “Today we will be looking at a study from the CDC and discussing five tips to potentially prolong your life. The Centers for Disease Control has discussed if an adherence to certain behaviors could lead to a decline in deaths from cardiovascular disease. To measure this they used participants from the National Health and Nutrition Examination Survey containing 44,959 participants. The study examined them from 1988-1994, 1999-2004 and 2005-2010.” Ford ES, Zhao G, Tsai J, Li C. Low-risk lifestyle behaviors and all-cause mortality: findings from the National Health and Nutrition Examination Survey III Mortality Study. Am J Public Health. 2011;101(10):1922-1929. doi:10.2105/AJPH.2011.300167 https://pubmed.ncbi.nlm.nih.gov/21852630/
2/1/2020 – Top Five Tips To Manage Diabetes – A study released in The Journal of Biological Chemistry and reported on at LifeExtension.com discussed how researchers out of Washington University in St. Louis wanted to test the effect of vitamin D and its role in decreasing atherosclerosis, or the hardening of the arteries, in patients with type 2 diabetes. https://www.lifeextension.com/magazine/2018/3/reduce-risk-of-arterial-stiffness
2/1/2020 – Top Five Tips for Protecting Young Athletes – The author cites a study from the American Academy of Pediatrics that reports a steadily increasing trend in A.C.L. and meniscus tears in adolescent athletes and even those under 10 years old. https://pediatrics.aappublications.org/content/pediatrics/139/3/e20161877.full.pdf
2/1/2020 – Top Five Reasons People Exercise – The American College of Sports Medicine recommends that aerobic exercise should be between three-to-five times per week. Depending on intensity of the workout, each session should last between 20 to 60 https://www.acsm.org/read-research/trending-topics-resource-pages/physical-activity-guidelines
2/1/2020 – Top Five Nutrients For A Healthy Brain – “We read a great article in the New York Times that reviewed a clinical study on brain function in the older population. The outcome of the study reaffirmed that nutrition plays an extremely important role in how the body functions as a whole. The author reports that the study will be featured in the January 24 issue of Neurology. The study was conducted by Gene Bowman” Bowman GL, Silbert LC, Howieson D, et al. Nutrient biomarker patterns, cognitive function, and MRI measures of brain aging. Neurology. 2012;78(4):241-249.doi:10.1212/WNL.0b013e3182436598 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280054/
2/1/2020 – Top Five Health Benefits of Olives – An article that appeared this month on Life Extension featured olives in one of their health reports. As they reported, the top five health benefits of olives https://www.lifeextension.com/magazine/2013/6/unexpected-benefits-of-olive-leaf-extract
2/1/2020 – Top Five Foods for Vitamins B1 and B6 – A really interesting study was highlighted on Life Extension online that discussed the possible link between vitamins B1 and B6 and a lower risk of dying. The study was from the Taiwan National Health Research Institutes and Monash University in Australia. https://www.lifeextension.com/newsletter/2012/8/higher-vitamin-b1-and-b6-status-linked-with-lower-risk-of-dying-over-eight-year-period
2/1/2020 – Top Five Foods Containing Lycopene – study released from the medical journal Neurology and featured on Life Extension suggests that lycopene may reduce the risk of stroke, especially for middle-aged men. This could be an extremely helpful study not only for reducing stroke risk, but also important for your overall health. https://pubmed.ncbi.nlm.nih.gov/23045517/
2/1/2020 – Top Five Foods Containing Choline – A fascinating study featured in Life Extension could be very important to expecting mothers. Researchers at Cornell University wanted to see the effects of increased levels of choline on the babies of expectant mothers. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722688/
2/1/2020 – Top Five Food Sources of Vitamin D – A study in the American Heart Association’s journal Stroke, and reported online at LifeExtension, showed that Vitamin D may be more Important than first thought in fighting strokes. https://www.lifeextension.com/protocols/heart-circulatory/atherosclerosis-and-cardiovascular-disease
2/1/2020 – Top Five Food Sources For Calcium – “The American Journal of Clinical Nutrition concluded that there is no clinical link between calcium intake and heart disease. Researchers with the Farmingham Offspring Study included 588 men and 690 women who were evaluated for calcium intake through” Samelson EJ, Booth SL, Fox CS, et al. Calcium intake is not associated with increased coronary artery calcification: the Framingham Study. Am J Clin Nutr. 2012;96(6):1274-1280. doi:10.3945/ajcn.112.044230 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497924/
1/14/2021 – The Rehabilitation Process and Nutrition’s Major Role – According to Nutritional Considerations and Strategies to Facilitate Injury Recovery and Rehabilitation, which appeared in the September 2020 issue of the Journal of Athletic Training, “once an injury is sustained, a cascade of inflammatory, immune, and metabolic responses is activated, resulting in a hypermetabolic state. To support this hypermetabolic state and the injury-healing process, significant macro- and micronutrient support is required.” https://meridian.allenpress.com/jat/article/55/9/918/444137/Nutritional-Considerations-and-Strategies-to
1/20/2021 – Maximum Wellness, Episode 82: Targeting the Optimum Fat Burning Heart Rate Training Range – According to research – “Fat Oxidation Rate As a Function of Plasma Lipid and Hormone Response in Endurance Athletes” – which appeared in the January 2020 issue of theJournal of Strength and Conditioning Research” Soria M, Ansón M, Lou-Bonafonte JM, Andrés-Otero MJ, Puente JJ, Escanero J. Fat Oxidation Rate as a Function of Plasma Lipid and Hormone Response in Endurance Athletes. J Strength Cond Res. 2020;34(1):104-113. doi:10.1519/JSC.0000000000003034 https://pubmed.ncbi.nlm.nih.gov/30707143/
12/18/2020 – Research Confirms Optimum Vitamin D Blood Values – “According to research from the Vitamin D, Skin, and Bone Laboratory, Section Endocrinology, Diabetes, Nutrition, and Weight Management, Boston University School of Medicine, and the Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok.” Charoenngam N, Holick MF. Immunologic Effects of Vitamin D on Human Health and Disease. Nutrients. 2020; 12(7):2097. https://doi.org/10.3390/nu12072097 https://www.mdpi.com/2072-6643/12/7/2097
1/8/2021 – Protein Sources for Athletic Performance – based the 2014 research of Helms/Aragon & Fitschen. In the April 2015 edition of the Strength and Conditioning Journal (National Strength & Conditioning Association), a research paper – “Protein Applications in https://jissn.biomedcentral.com/articles/10.1186/1550-2783-11-20
1/8/2021 – Omega 3s versus Obesity and Insulin Resistance – Fatty Acids Alleviate Adipose Tissue Inflammation and Insulin Resistance: Mechanistic Insights” – which appeared in Advances in Nutrition in July of 2011. https://academic.oup.com/advances/article/2/4/304/4591498
1/8/2021 – Magnesium Intake and its Associations with Diabetes – “The Journal of Human Nutrition & Food Science concluded through a study that there appears to be “an association between higher magnesium intake and improved diabetes outcomes and metabolic.”” Barbagallo M, Dominguez LJ. Magnesium and type 2 diabetes. World J Diabetes. 2015;6(10):1152-1157. doi:10.4239/wjd.v6.i10.1152 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549665/
1/8/2021 – Higher Protein Intake Improves Cardiometabolic Risk – According to a research paper published in the Journal of Nutritional, “Diets that promote protein intake above the RDA [0.8 g/kg body weight (BW)] are extremely popular. https://pubs.rsc.org/en/content/articlelanding/2016/FO/C5FO01530H#!divAbstract
1/8/2021 – Go Farther and Harder with Caffeine – In an April 2013 study published by the American College of Sports Medicine, researchers took 10 highly trained male cross-country skiers and had them perform both a placebo and caffeine trial run using a randomized, double-blind, crossover design. https://journals.lww.com/acsm-msse/Fulltext/2013/11000/Caffeine_Increases_Performance_in_Cross_country.20.aspx
1/8/2021 – Fruits and Vegetables May Lead to Healthier Arteries – The study, authored by Minneapolis Heart Institute cardiologist Dr. Michael Miedema and featured on Life Extension online, followed the fruit and vegetable consumption of women in the 20’s for https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.114.012562?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed&
12/29/2020 – Fish Oil Lowers Cardiovascular Disease Risk – Medscape.com reported in March 2020 that researchers from the Department of Epidemiology, School of Public Health, Southern Medical University in China, determined that, “habitual fish oil supplementation was associated with a 13% lower risk for all-cause https://www.medscape.com/viewarticle/926684
12/18/2020 – COVID-19: Prioritizing a Nutrient Based Immune Defense – “According to Inadequacy of Immune Health Nutrients: Intakes in US Adults, the 2005 – 2006 NHANES (National Health and Nutrition Examination Surveys) – which appeared in the August issue of the online, peer-reviewed journal Nutrients” Reider CA, Chung RY, Devarshi PP, Grant RW, Hazels Mitmesser S. Inadequacy of Immune Health Nutrients: Intakes in US Adults, the 2005-2016 NHANES. Nutrients. 2020;12(6):1735. Published 2020 Jun 10. doi:10.3390/nu12061735 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352522/
12/18/2020 – COVID-19: Immune Support Update 2 – 19, Thailand Medical News recently reported that, “a new research study by researchers from Wenzhou Medical University in Zhejiang province lead by Dr. Don Chen https://www.medrxiv.org/content/10.1101/2020.02.27.20028530v1.full-text
1/6/2021 – Causes & Risk to Sports-Related Injuries – “According to the Journal of Sport and Health Science, hamstring strains are one of the most common sports injuries.” Ernlund L, Vieira LA. Hamstring injuries: update article. Rev Bras Ortop. 2017;52(4):373-382. Published 2017 Aug 1. doi:10.1016/j.rboe.2017.05.005 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582808/
7/6/2020 – Can Sleep Durations Affect Mortality? – “According to Association of Longitudinal Patterns of Habitual Sleep Duration with Risk of Cardiovascular Events and All-Cause Mortality, which appeared on JAMA Network Open in April of 2020,” Wang YH, Wang J, Chen SH, et al. Association of Longitudinal Patterns of Habitual Sleep Duration With Risk of Cardiovascular Events and All-Cause Mortality. JAMA Netw Open. 2020;3(5):e205246. Published 2020 May 1. doi:10.1001/jamanetworkopen.2020.5246 https://pubmed.ncbi.nlm.nih.gov/32442289/
