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Nutrition Topics Nutrition ProductsRecipesVitamins & MineralsWeight Management Latest in Nutrition WEB SERIES Maximum Wellness Workout Wednesday LATEST IN WEB SERIES Shop SHOP Brain & Heart Health Bundle & Save CBD Diet & Energy Essential Oils Fitness Accessories Immunity Joints Support & Omegas Lab Tests Men's Health Mocktails Performance Pre-Workout Probiotics & Digestion Protein Targeted Health Vitamins & Minerals Women's Health LATEST PRODUCTS Fitness Fitness Topics Performance Recovery Fitness Essential Amino Acids Support Muscle Protein Synthesis Fitness Maximizing Recovery After Training & Competition Fitness The Keto Diet Plan May Benefit Body Builders Fitness High Intensity Interval Exercise VS Moderate Intensity, Continuous Training Health & Wellness Top Five Tips to Avoid Training too Much Fitness Vitamins and Minerals to Improve Adolescent Fitness Latest in Fitness Health & Wellness Health & Wellness Topics Health & Wellness Products Immunity Men's Health Women's Health Health & Wellness Nutritional Factors May Modify Risk to Covid-19 Health & Wellness COVID-19: Vitamin D May Modulate Risk & Severity Health & Wellness Fish Oil Lowers Cardiovascular Disease Risk Health & Wellness Teenagers Top Five Foods for Success Health & Wellness Research Confirms Optimum Vitamin D Blood Values Vitamins & Minerals Are Multivitamins Right for You? Latest in Health & Wellness Nutrition Nutrition Topics Nutrition Products Recipes Vitamins & Minerals Weight Management Nutrition Top Five Foods to Fight Inflammation Recipes High Protein Blue Berry Pancakes Nutrition The Top Five Healthy Foods for Women High Protein Recipes Egg & Turkey Stuffed Peppers Low Carb Recipes Hearty Breakfast Sausage Nutrition Are Cleansing Supplements Right for You? Latest in Nutrition WEB SERIES WEB SERIESpodcastsMaximum Wellness podcastsRecipes podcastsWorkout Wednesday LATEST IN WEB SERIES Maximum Wellness Maximum Wellness, Episode 53: Mediterranean Diet Helps with Non-Alcoholic Fatty Liver Disease Date July 1, 2020 Non-alcoholic fatty liver disease (NAFLD) is defined in the literature, as an accumulation of liver fat in individuals, who are not consumers of excessive amounts of alcohol—more than 20 grams per day for women and less than 30 for men. According to research—”Mediterranean Diet and NAFLD: What We know and Questions That Still Need to be Answered”—which appeared in the December 2019 online issue of the journal Nutrients—”NAFLD encompasses different clinical scenarios, from the simple accumulation of fat in the liver (steatosis), to steatohepatitis (NASH), cirrhosis, and its complications.” The research points out that the presence of liver steatosis globally has hit 25% of the population—with 46% here in the United States. Liver steatosis represents a reversible condition caused by an accumulation of triglyceride fat in liver cells. The Merckmanual.com says that NASH is defined as the presence of fat leading to lipo-toxicity and inflammatory damage to hepatocytes (liver cells). Since there no approved drug treatment methods to address the global impact of NAFLD and its manifestations, addressing systemic and visceral (fat in midsection) obesity and the associated inflammation is an appropriate place to start. The Mediterranean Diet (MD)—a plant-based eating plan with a high ratio of mono-unsaturated fatty acids (MUFA), representing 30-40% of the daily caloric intake—is rich in olive oil, nuts, vegetables, whole grains, legumes, fish (high sources of omega-3 fatty acids) and other seafood, while low in meat and dairy products, and moderate alcohol consumption (mainly rede wine)—all anti-inflammatory in nature. From a dietary pyramid perspective, the MD breaks out as follows: protein (legumes, fish & meat) constitute 25%, vegetables & fruits 50%, grains, rice, and pasta 25%—with 1 glass of red wine and 1-2 servings of olive oil. The Italian study investigators comment that, “a diet (like the MD) rich in omega-3-fatty acids has been shown to be protective against fatty liver as it prevents hepatic fat accumulation and reduces hepatic steatosis. An additional benefit of the MD on fatty liver disease is related to its low content of refined sugars, fructose, and high content of complex carbohydrates and fibers.” Surprisingly, the researchers note that, “the MD consents to a moderate amount of alcoholic units per day. Although there is a lack of studies with convincing evidence to support the benefits versus harms of ethanol intake, light alcohol intake seems safe in NAFLD non-cirrhotic patients.” A recent retrospective study the Italians cite on the effects of alcohol consumption on survival in NAFLD-patients, “reported that drinking 0.5-1.5 drinks per day decreases the risk of overall mortality by 41%.” I personally find that research suspect. The MD is rich in high-fiber whole grains, which may be beneficial in NAFLD patients, since they have less energy density and induce more satiety (hunger satisfaction) than refined carbohydrates. The whole grains also modulate gut microbiota through its prebiotic (food for the healthy gut bacteria), which may play a role in the pathogenesis of NAFLD and its progression. The Italians conclude by commenting that, “MD has recently been suggested as the diet of choice for NAFLD treatment, but the evidence behind this recommendation is very low, as most of the studies that have addressed this issue included few patients, differed in the inclusion/exclusion criteria, the methods by which steatosis was measured, and in the measurement of outcomes.” Sign up for Mackie Mail, on mackieshilstone.com—my free, weekly wellness update with Fitness in Small Spaces 90-second videos Monday, my Maximum Wellness podcast and script on Wednesday, and, on Friday you receive my WWL/WUPL 3-minute Workout Wednesday segment. You can also contact firstname.lastname@example.org should you desire nutrition product shipped or locally delivered to your door. 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