Benefits Of Each Ingredient

Vitamin E

• Supports immune function, cognitive health, cardiovascular health, and bone health (204,205,206,207,208)
• Supports immune health via neutralizing free radicals and reactive oxygen species, and increased T lymphocyte-mediated immune function (204).
• Supports cardiovascular health via reduced cholesterol (204).
• Supports cognitive function via reduced oxidative stress, inflammation, and DNA damage of neuronal tissues (208).

Vitamin B6

• Serves as a cofactor in more than 150 enzymatic reactions associated in blood sugar regulation, immunity, cardiovascular function, neuronal health, metabolic, and digestive health (38, 40).
• Reduces plasma glucose (blood sugar levels) via by inhibiting the activity of small-intestinal α-glucosidases (enzymes associated with glucose metabolism) (39).
• Functions as an antioxidant by counteracting the formation of reactive oxygen species (inflammatory markers) and advanced glycation end-products (38,40).
• May support blood sugar regulation in women with gestational diabetes (40).
• Cofactor for enzymes involved in DNA metabolism (40).

Zinc

• Supports immune function, skin health, cognitive function, and vision (172,173).
• Supports stimulation of the innate and adaptive immune system (172,173).
• Supports the activation of lymphocytes and activation of innate and T cell-mediated immunity (172,173).
• Supports cognitive function by modulation of neuronal signaling in areas of the brain associated with memory and learning (hippocampus) (172,173).

Copper

• Supports healthy blood sugar levels, energy metabolism and cholesterol management (143,144).

Selenium

• Supports antioxidant function, cardiovascular health, cognitive function, thyroid health, and immune health (145, 146).
• Combats atherosclerosis, high cholesterol (hypercholesterolemia), and type 1 diabetes (147).
• Supports thyroid health via decreased circulating thyroid autoantibodies in patients with chronic autoimmune thyroiditis (AIT) (146).
• Increases the activity of selenoproteins that decrease reactive oxygen species (inflammation), increases natural killer activity, and increases glutathione (master antioxidant) levels (145,147).

Saw Palmetto

• Supports prostate health, cardiovascular health, and increased hair growth (133,134).
• Supports prostate health via anti-androgenic and anti-inflammatory effects resulting in reduced Benign prostatic hyperplasia (134).

Pygeum Africanum

• Supports healthy testosterone levels, improves prostate health, and reduces chronic inflammation (18).

Red Raspberry

• A natural aromatic compound derived from raspberries enhancing fat oxidation(burning) and antioxidant protective mechanisms (21).
• Supports suppression of lipid accumulation (fat build-up) in adipocytes (fat cells) (21).
• Increases total antioxidant capacity by increasing enzymes associated with decreasing reactive oxygen species (superoxide dismutase) (22).
• Increases natural production of master antioxidant L-Glutathione (22).

Graviola

• Supports antioxidant function, reduces inflammation, and aids an antimicrobial agent (186,187).
• Supports antioxidant function via 200 phytochemicals and high concentration of alkaloids (186,187).
• Combats inflammation via reduced inflammatory cytokines (markers of inflammation (186,187).

Green Tea Extract

• Potent polyphenolic antioxidant that supports blood pressure, insulin sensitivity, and metabolic health (26).
• High in ECGC (epigallocatechin gallate) (26).
• ECGC is shown to reduce body fat mass, increase fat oxidation(burning) and increase caloric expenditure during exercise (25).
• Potent anti-inflammatory compound supporting glutathione production and inhibition of pro-inflammatory markers (cytokines) (26).
• Reduces oxidative stress (chronic inflammation in the body) (26).

Cat’s Claw

• Supports respiratory health and combats neurodegenerative disease and inflammation (188).
• Supports respiratory health via reduced prevalence of respiratory infections entering lung cells (inhibition of ACE2 receptor protein docking) (188).

Broccoli Extract

• Supports antioxidant activity due to the high content of polyphenols and flavonoids (antioxidants) (190).

Tomato Extract/Lycopene

• Supports prostate health, cardiovascular support, antioxidant, anti-inflammatory, and chemoprotective properties against cancer (191,192, 193).
• Combats inflammation via scavenging of free radicals and reduced oxidative damage of DNA. (191,192,193).
• Combats carcinogenesis via carcinogen-metabolizing enzymes, apoptosis (cancer cell death), anti-proliferation, pro-differentiation, and anti-lipid peroxidation activities. (193).
• Inhibits phosphorylation of anti-oncogenes such as p53 and Rb. It also inhibits G0/G1 and S-phase of the cell cycle (193).

Stinging Nettle

• Supports blood sugar regulation and urinary health.

Maitake, Reishi, & Shitake

• Supports immune health, antioxidant activity, balanced estrogen levels, antiviral support, antibacterial, reduced stress, improved exercise performance, and blood sugar regulation (194,195).
• Supports immune health via high concentrations of betagluxans which increase natural killer cell activity and t-cell-mediated immunity (194).
• Reduces the concentration of inflammatory cytokines IL-1α, IL-6, IL-10 and TNF-a (inflammation markers) in macrophages (immune cells) (194).
• High in the amino acid L-Ergothioneine (mainly found in mushrooms) that supports longevity, decreases chronic inflammation, and antioxidant activity (194).

Quercetin

• Supports antioxidant, anti-inflammatory, immune system defense, reduced homocysteine (allergies), reduced triglycerides, and combats bacterial infections (114,115,116).
• Supports immune health via reduced c-reactive protein (major inflammatory biomarker), increased neutrophil chemotaxis, macrophage phagocytosis, NK cell lytic activity and mitogen-stimulated lymphocyte (white blood cell) proliferation (114).

Juniper

• Supports urinary health via the decreased prevalence of urinary tract infections.

Uva Ursi

• Supports urinary health via the decreased prevalence of urinary tract infections (196).

Pumpkin Seed

• Supports urinary health, and immune function (175).
• Substantial improvement in BPH/LUTS. The observed symptom relief is accompanied by a clinically significant improvement in IPSS-related (175).