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Nutrition Topics Nutrition ProductsRecipesVitamins & MineralsWeight Management Latest in Nutrition WEB SERIES Maximum Wellness Workout Wednesday LATEST IN WEB SERIES Shop SHOP Bars & Drinks Bundle & Save Diet & Energy Essential Oils Fitness Accessories Joints Support & Omegas Lab Tests Men's Health On Sale Products Performance Probiotics & Digestion Protein Superfoods & Plant Based Targeted Health Training Programs Vitamins & Minerals Women's Health LATEST PRODUCTS Fitness Fitness Topics Performance Recovery Fitness Essential Amino Acids Support Muscle Protein Synthesis Fitness Maximizing Recovery After Training & Competition Fitness The Keto Diet Plan May Benefit Body Builders Fitness High Intensity Interval Exercise VS Moderate Intensity, Continuous Training Health & Wellness Top Five Tips to Avoid Training too Much Fitness Vitamins and Minerals to Improve Adolescent Fitness Latest in Fitness Health & Wellness Health & Wellness Topics Health & Wellness Products Immunity Men's Health Women's Health Health & Wellness Nutritional Factors May Modify Risk to Covid-19 Health & Wellness COVID-19: Vitamin D May Modulate Risk & Severity Health & Wellness Fish Oil Lowers Cardiovascular Disease Risk Health & Wellness Teenagers Top Five Foods for Success Health & Wellness Research Confirms Optimum Vitamin D Blood Values Vitamins & Minerals Are Multivitamins Right for You? Latest in Health & Wellness Nutrition Nutrition Topics Nutrition Products Recipes Vitamins & Minerals Weight Management Nutrition Top Five Foods to Fight Inflammation Recipes High Protein Blue Berry Pancakes Nutrition The Top Five Healthy Foods for Women High Protein Recipes Egg & Turkey Stuffed Peppers Low Carb Recipes Hearty Breakfast Sausage Nutrition Are Cleansing Supplements Right for You? Latest in Nutrition WEB SERIES WEB SERIESpodcastsMaximum Wellness podcastsWorkout Wednesday LATEST IN WEB SERIES Maximum Wellness Maximum Wellness, Episode 96: Resistance Exercise Improves Post-Meal Glucose Levels in Prediabetic Men Date April 28, 2021 Prediabetes, which affects over 86 million adults in the United States, is established by achieving a fasting blood sugar in the range of 100-125 mg/dl and / or an impaired glucose tolerance test. The good news is that prediabetes can be, in many cases, returned to a normal blood sugar status, with appropriate, positive lifestyle changes, that involve a combination of dietary restriction and exercise. There is also evidence that type 2 diabetes may be reversed with more invasive strategies – such as bariatric surgery – in a select, overweight/viscerally fat population. According to research – a “Single Bout of Premeal Resistance Exercise Improves Postprandial Glucose Metabolism in Obese Men with Prediabetes” – which appeared in the April 2021 issue of Medicine & Science in Sports & Exercise, the (2002) Diabetes Prevention Program Research Study demonstrated that lifestyle interventions, which targeted a 7% weight loss with 150 minutes per week of moderate-intensity endurance exercise, “reduced the incidence of T2D by 58% and was significantly more effective than treatment with metformin alone in individuals with prediabetes.” Yet there is insufficient research to establish the effects of resistance exercise (RE) on glucose metabolism in prediabetics. Some evidence has demonstrated that, in older, overweight subjects with prediabetes, twelve weeks of RE improved glucose tolerance, but not insulin sensitivity, during an oral glucose tolerance test. The Medicine & Science researchers, from Washington University School of Medicine in St. Louis and the Department of Orthopedics, Duke University in North Carolina, chose to establish the effects of a single bout of RE on post-meal (postprandial) glucose metabolism, after a mixed meal in obese, sedentary men with prediabetes. Ten sedentary, prediabetic, obese men enrolled in the randomized, cross-over study. After an overnight fast, the participants were guided to complete a single session of RE – seven exercises, 3 sets of 10-12 repetitions at eighty percent of their predetermined maximum strength (1-rep max), or an equivalent rest period. After the RE, the subjects consumed a mixed test meal, while simultaneously having an intravenous glucose infusion, to establish their basal and post-meal rate of glucose appearance and disappearance from their plasma, insulin insensitivity, and an insulinogenic index to measure beta cell function in the pancreas. “Skeletal muscle biopsies were obtained 90 min post-meal to evaluate pyruvate-supported and maximal mitochondrial respiration. Whole-body carbohydrate oxidation was assessed using indirect calorimetry,” according to the researchers. The researchers concluded that, “a single bout of RE moderately reduced the glycemic response to a mixed meal, significantly improved insulin sensitivity, and reduced the glucose-normalized insulin response in obese, middle-age men with prediabetes.” It was also noted that, “there were limited effects on postprandial glucose clearance, insulinogenic index, whole-body carbohydrate oxidation, or skeletal muscle pyruvate-supported respiration.” As with any such research, with a small group of subjects, additional research is needed to determine how RE brings about positive changes after a meal, which typically in the US, is high in fat and sugar. Before you embark on changes to your exercise or diet, especially if you are a male, who is sedentary and obese, with known or undiagnosed prediabetes or type 1 or 2 diabetes, check with your primary care physician.